Lecture 23 Nov 2001, Per Kraulis
The list of currently determined genomes is growing rapidly, probably at an exponential rate. This means that it is beginning to be difficult to keep updated. Luckily, there are a number of web sites that (try to) keep track of the status of the various genome projects. Here are links to some of them:
There are a number of web sites that focus on data for specific genomes. Usually, these sites contain more data than just the DNA sequence of the genome, such as predicted transcripts (ORFs, Open Reading Frames), verified transcripts and tentative identifications or classifications of the predicted proteins.
Here is a table of a few complete genomes, with information and links. Please note that the number of ORFs given below for each genome is tentative. The numbers depend on the exact procedure used to identify known genes and predict previously unknown genes (see the section Analysing a genome).
|Haemophilus influenzae||Bacterial||1.83 Mb, 1850 ORFs||The Haemophilus influenzae Genome Database at TIGR.||The first genome of a free-living organism. 1995|
|Escherichia coli||Bacterial||4.64 Mb, 4289 ORFs||E.coli Genome Project University of Wisconsin-Madison||The most studied bacterium. 1997|
|Rickettsia prowazekii||Bacterial||1.11 Mb, 834 ORFs||The first genome to be sequenced in Sweden (Siv Andersson, Uppsala). 1998|
|Methanococcus jannaschii||Archaeal||1.66 Mb, 1750 ORFs||The Methanococcus jannaschii Genome Database at TIGR.||The first sequenced Archaea. 1996|
|Saccharomyces cerevisiae||Eukaryote||12.1 Mb (16 chromosomes), 6294 ORFs||SGD, MIPS yeast DB||The first sequenced eukaryote. 1997|
|Caenorhabditis elegans||Eukaryote, nematode||97 Mb (6 chromosomes), 19,099 ORFs||WormBase, C. elegans Genome Project||The first sequenced multicellular organism.|
|Drosophila melanogaster||Eukaryote, insect||137 Mb (excluding heterochromatin, 6 chromosomes), 14,100 ORFs||BDGP, Flybase||Celera Corp, publicly available. 2000|
|Homo sapiens||Eukaryote, primate||3000 Mb (24 chromosomes), ? ORFs||HGP at Sanger, HGP at Oak Ridge||Rough draft exists. Not yet finished, except for chromosomes 21 and 22.|